Asthma is a chronic inflammatory disorder of the airways characterized by an obstruction of airflow, which may be completely or partially reversed with or without specific therapy. Asthma attacks can be related to changes in atmospheric temperature, barometric pressure and the quality of air. In some patients, fungi, bacteria or parasites may be responsible for asthma condition. Asthma is having the subtype such as allergic and nonallergic. Salbutamol sulphate is widely used as bronchodilator to manage asthma and other chronic obstructive airway disease. More recently, orally disintegration films (or strips) have come to light. As the mucoadhesive buccal films (or strips) are small in size and thickness, it has improved patient compliance, compared to tablets. The natural and synthetic polymers are used in the formulation of fast dissolving oral strip and were prepared by solvent casting method. The strips which were prepared using combination of polymers (HPMC E-15 with maltodextrin) showed excellent dissolution profile compared to strips prepared with individual polymers and mannitol used as a solubiliser. It was observed from the results that, A-3 and C-3 formulations showed maximum dissolution rate of about 99% in 15 min, thus it was concluded that designed films showed rapid disintegration and immediate drug release.
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